When a mutation substitutes for a single codon, which position is most likely to change the amino acid associated with that codon? Why is that?

Answers

Answer 1

Answer:

In most cases the codons encoding for a specific amino acid differ only by a single nucleotide (typically the third one). However, serine is unique among the 20 amino acids in that it is encoded by two disjoint sets of codons that require a tandem substitution of two nucleotides to switch between the two sets, one comprised of the codons TCT, TCC, TCA and TCG (TCN, denoted set S′) and the other set includes only two codons - AGT and AGC (AGY, denoted set S′′)1. The two sets of codons encoding serine cannot be connected through a single point mutation1. The serine’s codon structure allows it to participate in two separate substitution patterns, each of which conserves different amino acid characteristics. The S′′ single mutation transition substitution category includes the amino acids serine, in addition to transition neighbors2,3,4 glycine (G), and asparagine (N). In contrast, the S′ single mutation transition substitution category includes serine, proline (P), and alanine (A)3,5,6 (Fig. 1). The substitution of S′ to amino acids P and A occur by a single mutation at the first codon position. The substitution from serine to threonine (T) is not included either of the substitution sets, as it can be a result of a single nucleotide change from either S′ of S″. While the amino acid substitution derived from S′ are enriched in conserved β-turns3,6,7, those derived from S″ are generally of a neutral hydrophobicity (i.e., amino acids that are neither strongly hydrophobic or hydrophilic)3,6.

Explanation:


Related Questions

URGENT, PLEASE!

Which process do you think offers a greater chance of nondisjunction—mitosis or meiosis?

Answers

meiosis.............

The biological process which offers a greater chance of nondisjunction is: meiosis.

Nondisjunction can be defined as a situation in which a pair of hom-ologous chromosomes within the cells of a living organism fails to segregate (separate), thereby, leading to the production of unidentical daughter cells with an abnormal number of chromosomes.

Meiosis is a type of cell division (duplication) that occurs in all body cells found in living organisms, through which a single cell segregate (separate) twice (2) to produce four (4) haploid cells (gamete).

Hence, meiosis is offers a greater chance of nondisjunction because the single cell segregate (separate) more than once, leading to the production of unidentical daughter cells with an abnormal number of chromosomes.

Read more: https://brainly.com/question/12103012

can u get this right?

Answers

Answer:

New

Explanation:

because facings the dun the dide facing earth id getting no sunlight

the answer is new moon!
(it’s right next to the sun)

Cardiomyopathy is a chronic disease of the heart muscle characterized by muscle that is thick, stiff, weak, and irritable. It can result in symptoms such as _____
heart failure.

Answers

I believe the answer is congestive heart failure.
Other Questions
In the diagram, x is a negative number. and it is closer to zero than y.y is a positive number. which expression must be negative Help me pls! ( Area of Composite Figures) On August 1, Year 1, SuperCool Software (SCS) began developing a software program to allow individuals to customize their investment portfolios. Technological feasibility was established on January 31st of year 2, and the program was available for release on March 31, year 2. Development costs were incurred as follows:August 1 through December 31, Year 1 $ 4,000,000January 1 through January 31, Year 2 600,000February 1 through March 31, Year 2 900,000SCS expects a useful life of five years for the software and total revenues of $10,000,000 during that time. During Year 2, SCS recognized $2,000,000 in revenue, included in the $10,000,000 total revenue estimate.Calculate the required amortization for Year 2 (Hint: calculate using both methods, choose the greater number) Jonah and Graham are working together. Jonah claims that (x+y)^2 = x^2+y^2. Graham is sure Jonah is wrong, but he cannot figure out how to show it. a.) Help Graham find as many ways as poissible to convince Jonah that he is incorrect. How can he rewrite (x+y)^2 correctly? My teacher wants me to answer questions 1-10 with work shown. It can be any kind of work as long as it shows how you got the answers. The electoral College system is an example of which type of government Which of the following is not something that the circulatory system is responsible for?A. bringing carbon dioxide to your cellsB. bringing nutrients to your cellsC. bringing oxygen to your cells Which of these happens when you add the prefix mis- to the word spell?A. The prefix is followed by a hyphen.B. The last /is dropped.C. The word becomes misspell.D. The s is dropped from spell. 6.A. [tex]-\frac{1}{5}[/tex]B. [tex]\frac{x1}{5}[/tex]C. 5D. 5 Which equation represents a function? A larger number is double the sum of 3 and a smaller number. The larger number is 2 less than 3 times the smaller number. If y represents the larger number and x represents the smaller number, which equations model the situation? Check all that apply. What method of treatment did doctors use to remove the humors they believed caused the plague in their patients? No one knows the true origin of ice-cream, but the first published ice-cream recipe appears in "Mrs. Mary Eales's Receipts," a cook book that was printed in London in 1718. Sometime around 1832, an African American confectioner named Augustus Jackson created multiple ice cream recipes and invented a superior technique to manufacture ice cream. Ice cream soda was invented around 1874, but the real breakthrough may have been at the 1904 World's Fair in St. Louis, Missouri, when the American ice-cream cone was unveiled! a. Problem and solution b. Cause and effect c. Chronological d. Spatial / descriptive e. Sequence / process I will make brainliest Which of the following was a key difference between the non-violent protest movement and the Black Power Movement?a. Strong leader shipb. stance on integrationc. student participationd. national attention summarize the poem ini rere by Niyi osundare The modern day country ofwas established from the remnants of the Ottoman Empire.a. Iraqb. Egyptc. Turkeyd. Iran Kylie is selling gift bags and wrapping paper for a school fundraiser. Mrs. Jones orders 4 gift bags and 3 rolls of wrapping paper for $47.50. Mrs. Kim orders 7 gift bags and 1 roll of wrapping paper for $47.00. Mr. Burnett wants to order 3 gift bags and 5 rolls of wrapping paper. How much is Mr. Burnetts order?b = Gift Bagp = Wrapping PaperWhich system represents the problem situation? Use the figure below and 2-3 sentences to explain the following:The side opposite angle E is side ____?The side adjacent to angle E is side ____?The hypotenuse is side ____? HELP ASAP PLEASE NO LINKS Question 1(Multiple Choice Worth 3 points)(07.04)The solution to 6x = 48 is x =05060708