Phenytoin (sodium channel blocker) and ethosuximide (calcium channel blocker) are anti-seizure drugs that stop seizures from happening. These drugs work by inhibiting electrical impulses (action potentials) from occurring. Explain the importance of sodium and calcium channels on a neuron and and the reasons why action potentials do not occur when these channels are inhibited

Answers

Answer 1

Answer:

Phenytoin and ethosuximide are drugs that slow the recovery of the sodium channel during the inactivated state.

That is to say, they prolong the inactivation state of the channel, thus generating that in this way the neuron remains in resting potential and the action potential causing the epileptic attack is not triggered.

On the other hand, these drugs, according to the bibliography of the book "Golan, 3rd Edition, Principles of Pharmacology" have a use-dependent affect capacity, this means that those sodium channels that have more activity will be more affected, in this way Not only is epileptic shock avoided, but if the same happens independently in any neuron, it will not be able to propagate the action potential to its neighboring neurons, therefore the surrounding neurons will not be stimulated and will not be fulfilled. with the sudden rapid discharges that are the most dangerous in some cases of severe epilepsy.

It is important to understand that these drugs affect the ion channels responsible for exciting neurons, that is why by inhibiting them, a constant rest of these neurons is promoted, and they are unable to generate abrupt discharges and dissemination of the electric charge. among them generating epileptic shocks.

The ions in neurons are in charge of indicating or modulating the different neuronal states, if they are inactive, open or closed, they will directly affect the membrane potential, that is, the positive or negative charge of the neuron's membrane.

Explanation:

In order to finish completing the question, these drugs are excreted through the p450 protein, that is why if this excretion system becomes saturated because another drug is consumed that is excreted in the same way, these antiepileptics will remain longer in use. blood and in the body, generating a greater effect and enhancing adverse effects on the central nervous system.


Related Questions

Question 1
Choose all that apply: The cells in the human body that undergo mitosis are:
a
skin cells
Ser cells
liver cells
muscle cells

Answers

Answer:

liver skin and muscle cells

Explanation:

The cells in the human body that undergo mitosis are -

skin cells  liver cellsmuscle cells

Cell division is the process of producing new daughter cells from existing parent cells. The types of cell division include mitosis and meiosis.

Mitosis takes place in all eukaryotic cells which is a process of cell renewal and growth.Somatic cells, adult stem cells, and the cells in the embryo are the main cells that undergo mitosisSomatic cells are the regular cells in the body of multicellular organisms such as muscle, liver, and skin cells.

Thus, The cells in the human body that undergo mitosis are -

skin cells  liver cellsmuscle cells

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Using the food web below determine how many omnivores are present.​

Answers

Sea turtles, depending on the species, may eat seagrasses, algae, sponges, sea squirts, squid, shrimp, crabs, jellyfish, cuttlefish or sea cucumbers.

Fish can be omnivores, but they can also be herbivores and carnivores.

so basically there are 3 omnivores present

Select the correct answer. Which property of a substance can be determined using a pH indicator? A. acidity B. boiling point C. density D. electrical conductivity E. thermal conductivity

Answers

A. acidity
Acid and bass sides are the ph scale

Answer:

Acidity

Explanation: I took a test :)

Which organ system is responsible for coordination and integration of bodily functions as well as detecting changes inside and outside the body

Answers

The answer is endocrine system it works with the nervous to control the internal organs it helps with regulation of the body hormones growth and reproduction

According to the question, the answer is endocrine system it works with the nervous to control the internal organs it helps with regulation of the body hormones growth and reproduction.

What are 3 main functions of the endocrine system?Makes Hormones for Mood, Development, and Growth. Many different vital hormones are created and controlled within the endocrine system.Sends Hormones into Your Bloodstream.Regulates the Release of Hormones.

Thus,  endocrine system it works with the nervous to control the internal organs.

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Which of the following is nota cation? mercurous ion sulfate Ca 2+ iron(III) ion

Answers

I have no clue but I just want the thanks

Which factors involving the activities of people are a threat to biodiversity? pollution and succession habitat loss and predation poaching and habitat loss succession and poaching

Answers

Both poaching and habitat loss are a threat to biodiversity

Habitat loss refers to the destruction of natural ecosystems and consequent reduction in the amount of habitat available for the species living in a given area. Habitat loss is the greatest threat to ecosystems biodiversity and conservation worldwide by deteriorating natural areas and thereby reducing species distribution ranges. Habitat loss is primarily due to the expansion of human populations and human activities (i.e., mining, logging, trawling, industrial production, urbanization, etc.).  

Poaching refers to the illegal killing of wild animals for different reasons (e.g., meat, recreation, etc.), in violation of international, federal, state/provincial, or local laws. Poaching can drastically reduce the number of organisms in natural populations, thereby this human activity can reduce genetic diversity and eventually may lead to the extinction of natural populations/species.

In conclusion, both habitat loss and poaching can reduce the number of organisms, reduce biodiversity and eventually cause the extinction of natural populations.

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Answer:

C. Poaching and habitat loss

Explanation:

Test 100%

Also, good luck to whoever may need this anwer<3

Certain kinds of shells are always found in rock layers lower than layers with plant fossils. Dinosaur fossils show up only in layers above or with plant fossils what does this tell you about When these organisms lived

Answers

Answer:

This shows that once animals were on the surface there were plants for them to eat.

Dinosaur fossils show up only in layers above or with plant fossils. This shows that dinosaurs were animals that lived with plants and feed on plants.

What are fossils?

Fossils are the remains of plants, animals, and other substances that are preserved under the layers of rocks and earth. They are the preserved form that gives the knowledge of organism present in before times.

Dinosaurs lived 65 million years ago, but still, their bones and remains are found on earth. They were found with the fossils of plants, so this tells us that plants were also present at the time of their presence, and they fed on plants.

Thus, only strata above or in conjunction with plant fossils do dinosaur fossils appear. This demonstrates that dinosaurs were also plant-eating and lived with plants.

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2. How does the development of a nervous system and sense organs relate to increasing complexity of multicellular animals?

Answers

The development of nervous system and sense organs in multicellular organisms has led to evolution of species in a more complex manner.

Complexity of multicellular organisms

• The development of nervous system and sense organs has permitted for a greater level of perception and better equipped organisms.

• It has permitted the organisms to collect resources, react to their surroundings, and take advantage of their surroundings.

• This has resulted in the organisms to survive longer and accommodate into bigger types of body.

• Such amendments has thus permitted organisms to become more complex  and move up the food chain.

Thus, the development of nervous system and sense organs is associated with increasing complexity of multicellular animals.

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the all-or-none response of a neuron is similar to:

Answers

Answer:

The all-or-none law is a principle that states that the strength of a response of a nerve cell or muscle fiber is not dependent upon the strength of the stimulus. If a stimulus is above a certain threshold, a nerve or muscle fiber will fire.

The all-or-none response of a neuron is similar to a gun that either fires or doesn't. The correct option is B.

What is an all-or-none response?

According to the all-or-none principle, signal transmission between neurons is solely dependent on the initial threshold being met rather than the stimulus's intensity.

In other words, neurons either fully or totally avoid transmitting an impulse via the synapse to the subsequent neuron.

According to the all-or-none law, the strength of a nerve cell's or a muscle fiber's response is not influenced by the stimulus's intensity.

A nerve or muscle fiber will activate if a stimulus is present above a predetermined threshold.

Therefore, the correct option is B. a gun that either fires or doesn't.

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The question is incomplete. The missing options are given below:

A. a dimmer switch that can provide a wide range of light.

B. a gun that either fires or it doesn't.

C. a fuse that cannot overload the circuits.

D. a match that doesn't always light when it is struck.

You travel to Mars. You obtain a specimen that appears to have cells and responds to warm temperatures. Would this be classified as living or nonliving? living nonliving

Answers

I believe it might be living.

Answer:

LIVING

Explanation:

I took the test and got it right :)

What does the nucleus consist of

Answers

Answer:

If you are talking about atomic nucleus then it's consist of protons and neutrons.

Explanation:

But if you're talking about cell nucleus

Then,

It contains nuclear envelope, nuclear lamina, nucleolus, chromosomes, nucleoplasm .

Answer:

Protons and neurons.

Explanation:

The atomic nucleus consists of Protons and neurons

how Polar molecules can dissolves other polar molecules?

Answers

Explanation:

polar molecules do not have a symmetrical distribution of charge. one part of the molecule will be more negative and another part will be more positive which allows polar substances to dissolve each other.

The outer structure of the neuron is made of a

Answers

a semipermeable membrane

What organisms, other than bacteria, are able to perform nitrogen fixation?
a.
Viruses
c.
Algae
b.
Trees
d.
Protists

Answers

Answer:

Algae is able to perform nitrogen fixation.

Answer:

The answer is C.

Explanation:

I just took the test and the answer was c.

Bone does not amplify sound during speaking is _____________________

Answers

Answer:

Bone is a solid tissue, which resists a high impact of forces in its major axis.

The function of this fabric is not to transmit sounds, since it does not provide the elasticity, and the necessary elongation that is needed to generate the rope effect as in the case of muzzle cords.

Explanation:

The more rigid and less elastic the fabric is, the less sound it will transmit.

Sound strings, or mouth strings, are those that tighten, are flexible and resonate with different vibrations, in the case of bone tissue, sound vibrations are not influenced in their conformation because they do not have the ability to transmit them. .

The bone tissue, transmits impact forces or high newton levels, does not fulfill the function of transmitting vibrations and emitting sounds in terms of this type of vibrations and their frequencies.

are human skin cells from inside the mouth prokaryote or eukaryotic?

Answers

Answer:

Eukaryotic

Explanation:

I need help with and i will give you a branlist and it’s science

Answers

Answer:

B

Explanation:

Nitrogen has 7 protons

Which of the following are
factors in weathering and
erosion?
1. Precipitation
2. Temperature
3. Gravity
4. Wind
5. Deforestation
6. Acid

Answers

Answer:

please mark brainliest!

Explanation:

- Physical Weathering.

- Chemical Weathering.

- Water Erosion.

- Wind Erosion.

- Gravity.

Answer:

5. deforestation

4. wind

3. gravity

1. precipitation

What is an example of how technology is capable of changing society?

Answers

Technology can alter community through what becomes famous , like the cell phones that most people today have with them, and the fact that they have developed into phones with computer ability.

There are certain situation that arise as a outcome of a growing use of technology that impact the change, like Carpal Tunnel Syndrome causing shifts in the workplace, or a growing need for more technology like floppy discs changing to compact discs and DVD's.

How does technology change society?

Technology has a more favourable impact on humans or society in comparision of negative impact.

It makes our life is more easier and cite us by providing resources or tool that make our life much easier.

Thus, Technology can Alter society through what becomes famous, like the cell phones that most people today keep with them, and the fact that they have developed into phones with computer ability.

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Answer:

Technology can alter community through what becomes famous , like the cell phones that most people today have with them, and the fact that they have developed into phones with computer ability.

There are certain situation that arise as a outcome of a growing use of technology that impact the change, like Carpal Tunnel Syndrome causing shifts in the workplace, or a growing need for more technology like floppy discs changing to compact discs and DVD's.

Explanation: edgen 100%

To be characterized as a chordate, an organism must:________.
A) possess a backbone in both the larval and adult stages
B) display all four key characteristics of Chordata in both the larval and adult stages
C) display each of the four key characteristics of the chordates at some point in the life cycle
D) possess a backbone in at least one life stage.

Answers

Answer:

C) display each of the four key characteristics of the chordates at some point in the life cycle

Explanation:

To be characterized as a chordate, an organism must display each of the four key characteristics of the chordates at some point in the life cycle. Therefore, the correct option is C.

To be characterized as a chordate, an organism must display four key characteristics at some point in its life cycle.

These characteristics include having a notochord (a flexible rod-like structure), a dorsal hollow nerve cord, pharyngeal slits or pouches, and a tail.

It is not necessary for all four characteristics to be present simultaneously or in both the larval and adult stages. As long as the organism exhibits these characteristics at some stage of its life, it can be classified as a chordate.

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describe the impact of technology on the environment today

Answers

Technology has highly impacts our lives and with what we do. People use technology everyday, whether it’s tracking down a location or just simply calling someone. Without all the advance technology we have today our lives wouldn’t be as easy as it is right now.




what are the basic building blocks of fats?

Answers

Answer:

Fatty acids are the building blocks of the fat in our bodies and in the food we eat. During digestion, the body breaks down fats into fatty acids, which can then be absorbed into the blood. Fatty acid molecules are usually joined together in groups of three, forming a molecule called a triglyceride.

Which is a main function of lipids?
O providing energy storage
O transmitting genetic information
O forming bone and muscles
O fighting infection and disease

Answers

providing energy storage

Provide storage in energy

What are the roles of the two test
groups in this
investigation?
A. Both are experimental groups, and each
Individually shows the effect of the direction
B. Dhe is the experimental group and one is the
control group, and together they show the
ellect of the direction of light.
C. Both are control groups, but only Test Group)
shows the effect of the direction of light.
D. Both are experimental groups, but only Test
Group 1 shows the effect of the direction of
light

Answers

Answer:

We would also need to see the investigation to be able to help sorry

Which of the following types of cells suppress immune responses?a. Neutrophilsb. Plasma Cellsc. Macrophagesd. Regulatory T Cells

Answers

Answer:

The correct answer is d.

Explanation:

Regulatory T-cells are a class of T cells which are part of the immune system that suppresses immune response. They are called regulatory because they assist in "checking" the excesses/overreaction during immune response.

NOTE:

Neutrophils are phagocytic in nature; they ingest and destroy microorganisms or other foreign molecules.

Plasma cells synthesize antibodies which are produced in response to antigens. They are target foreign particles for digestion by other immune cells.

Macrophages are also phagocytic in nature usually found at sites of an infection.

Which is an example of mechanical weathering?
a. Feldspar reacts with the hydrogen in water to form clay, which crumbles easily.
b. A large rock falls from a cliff and breaks as it hits other rocks.
c. Oxygen reacts with iron, creating rust
d. Limestone dissolved by acid rain to create limestone caves

Answers

b. A large rock falls from a cliff and breaks as it hits other rocks

why do plant cells need chloroplast

Answers

Answer: Sample Response: Plant cells need chloroplasts so they can capture light energy to make food within the cells. Plant cells make their own food to produce energy that the cells use.

What are the Five characteristics of life

Answers

Answer:

The five characteristics of life are

Cells.

Obtain and Use Energy.

Reproduction.

Respond to the Environment.

Adapt/Evolve.

Explanation:

why is it harder for a mountain climber to breathe when they are the top of a tall mountain like mount everest

Answers

Answer:

Hmm.

Explanation:

Because the air gets thinner the higher the elevation (like on Mount Everest).

It is harder for a mountain climber to breath when they are thr top of a tall mountain because there is lack of oxygen in the high evalation like mount everest

Why is it dangerous or bad for babies to be born too small or too early?

Answers

It’s dangerous for babies to be born early because not all of the baby’s organs and bones may have not developed fully yet. Premature babies could also develop a bunch of different health problems such as asthma or feeding problems.
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Find the coordinates of the image after the given transformation.translation: 6 units right and 3 units down51-3, 3). C-1, 4), 14-2, -1)help me pls (-3)(16)=What is the question to this answer? PLEASE HELPPoint A is at (1,5) and point C is at (-5, 7).Find the coordinates of point B on AC such that AC is 6 times as long as AB. PLZZZZ HELP WILL GIVE BRAINLIST Plisss some one can help me!!!A project manager estimates that a project will takex hours to complete, where x > 100. The goal is forthe estimate to be within 10 hours of the time it willactually take to complete the project. If the managermeets the goal and it takes y hours to complete theproject, which of the following inequalitiesrepresents the relationship between the estimatedtime and the actual completion time? please I really need help if you help me I'll give you brainliest. PLEASE HELP THESE QUESTIONS ARE DUE TONIGHT 14 points well be given!!!and will be marked the brainiest ! A type of antisocial behavior is stalking. It generally involves the following behaviors except:a. Making verbal threats to the intended victim or a family memberb. Making threatening or harassing phone calls or hang-upsC. Sending unwanted love notes, flowers, and gifts after being told not to d. It is restricted to the famous A person is trying to quit chewing gum. They decide they will have 64 pieces in week 1, but each week have half as many as the week before. The function f represents the number of pieces of gum they will have in week n. What is a reasonable domain for this function? Explain your reasoning. Read the descriptions below and tell what each person's nationality is.Follow the model: Felipe vive en Europa. Es de Marid, Espaa. Es espaol.1. A ti te gusta la ciudad. Eres de Buenos Aires, Argentina. Eres2. Ramiro es de la capital de Puerto Rico. l es3. Pedro y yo somos de la misma ciudad, Santo Domingo, en la Repblica Dominicana. Somos4. Maricarmen y Elena son de Santiago, la capital de Chile. Ellas son5. No soy colombiano, soy de Mxico. Entonces, soy6. Ana Lisette es de la Ciudad de Guatemala. Ella es7. Luis y Ramn son de la Ciudad de Panam. Ellos son8. Ins es de Per, pero vive en Paraguay ahora. Ella es9. Ivan y yo vivimos en Miami, pero somos de Cuba. Somos10. T vives en los Estados Unidos, pero eres de Colombia. Eres11. Carla es de la capital de Costa Rica. Ella es12. Yo soy de San Antonio, Texas. Soysee Analyze the map below and answer the question that follows. A political map of the U S. Parts of the U S are labeled 1, 2, 3, and 4. 1 is in Nevada. 2 is in Minnesota and Iowa. 3 is in Texas. 4 is in the Southeast. In the United States, large quantities of oil and natural gas can be found in region _____ on the map above. A. 1 B. 2 C. 3 D. 4 Please select the best answer from the choices provided A B C D I need help with finding m & Im pretty sure exercise 6 is # 6 help please Do you agree with the following statement and why/why not:"it is every eligible American citizen's civic responsibility to vote"? When rounding to the nearest ten, what is is the least whole number that roundd to 840 what is the meaning of mean Which statement might be an accurate description of a serf's life?A.A serf could be bought and sold, much like a slave.B.A serf could move to a different manor if he or she desired.C.A serf was bound to the land upon which he or she worked.D.A serf who did well might be awarded a manor to rule. 20 pointsNEED HELP PLEASEEEE -4x+7=11 HELPP! pleaseeee Solve.f/5 - 24 = -28 f = Question 4 of 10 Which statement shows bias? A. The female doctor was surprisingly skilled at surgery. B. The doctor in the emergency room was rude to the nurse.C. The hospital has three female doctors and three male doctors. D. The surgeon who operated on Mom had a tattoo on his arm.