Let's suppose you were interested in developing drugs to prevent epigenetic changes that may contribute to cancer. What cellular proteins would be the target of your drugs?

Answers

Answer 1

Answer:

Potential targets:

1- DNA methyltransferases

2- Chromatin modifiers such as histone acetyltransferases, histone deacetylases, histone methyltransferases, etc.

3- Components of the RNA interference (RNAi) machinery such as Dicer, Argonaute, etc.

Explanation:

Epigenetics can be defined as the study of any heritable change in the phenotype that does not involve modifications in the DNA sequence. Epigenetic mechanisms can be classified into three major types: 1-DNA methylation, 2-histone modifications (e.g., acetylation, methylation, phosphorylation, etc), and 3-regulatory non-coding RNAs (e.g., miRNAs, lncRNAs, siRNAs, etc) that modulate target gene expression via the RNA interference pathway. There are different types of proteins that are involved in these complex epigenetic mechanisms, and those cited above represent only some examples that can be used as therapeutic targets.


Related Questions

The knee ________.
a. is completely enclosed by a strong articular capsule
b. is a multiaxial joint
c. has ligaments present inside as well as surrounding the articular capsule
d. is the simplest joint in the body

Answers

Answer:

The correct answer is: C) has ligaments present inside as well as surrounding the articular capsule.

Explanation:

The knee joint is a hinge (ginglymus) type synovial joint that is formed by three different bones: the femur, the tibia, and the patella.

Given the nature of the hinge joint, it should only allow flexion and extension, but it also grants a small degree of internal and external rotation. For this reason, the knee joint cannot be considered a multiaxial joint, since it only fully moves in one axis and slightly moves in a second one (this is why most people consider the knee joint a uniaxial joint, but some others say it is actually a biaxial one).

The knee joint isn't completely enclosed by a strong articular capsule. The knee joint is rather thin and it contains the patella, menisci, bursae, and ligaments of the knee.

The knee is not the simplest joint in the body. It is formed by three bones and there's also the menisci, which are fibrocartilaginous structures that help increase the stability of the joint and act as shock absorbers as well.

The knee does have ligaments both inside and outside the articular capsule. The intracapsular ligaments are two cruciate ligaments (one anterior and one posterior), which hold the tibia in place; the transverse ligament that connects both menisci; and the posterior and anterior meniscofemoral ligaments. The extracapsular ligaments are the patellar ligaments (connects the patella to the tibia), the two collateral ligaments (medial and fibular, one on each side of the knee, connecting the femur to the tibia and to the fibula, respectively), and the anterolateral ligament.

Structure of a Water molecule

Answers

Answer:

A water molecule consists of two hydrogen atoms and one oxygen atom. ... This molecular structure leads to hydrogen bonding, which is a stabilized structure in which a hydrogen atom is in a line between the oxygen atom on its own molecule and the oxygen on another molecule.

Explanation:

What molecule, when linked
with others, creates a single link
in the DNA chain?

Answers

Answer:Figure 4: Double-stranded DNA consists of two polynucleotide chains whose nitrogenous bases are connected by hydrogen bonds.

Explanation::))))))))))))))))))))))

What does this diagram represent?

Answers

It represents DNA since it is double stranded.

35 points please help science biology

Answers

Euglena are unicellular organisms classified into the Kingdom Protista, and the Phylum Euglenophyte. All euglena have chloroplasts and can make their own food by photosynthesis. They are not completely autotrophic though, euglena can also absorb food from their environment; euglena usually live in quiet ponds or puddles.

Euglena move by a flagellum (plural ‚ flagella), which is a long whip-like structure that acts like a little motor. The flagellum is located on the anterior (front) end, and twirls in such a way as to pull the cell through the water. It is attached at an inward pocket called the reservoir. Color the reservoir grey and the flagellum black.

The Euglena is unique in that it is both heterotrophic (must consume food) and autotrophic (can make its own food). Chloroplasts within the euglena trap sunlight that is used for photosynthesis, and can be seen as several rod like structures throughout the cell. Color the chloroplasts green. Euglena also have an eyespot at the anterior end that detects light, it can be seen near the reservoir. This helps the euglena find bright areas to gather sunlight to make their food. Color the eyespot red.Euglena can also gain nutrients by absorbing them across their cell membrane, hence they become heterotrophic when light is not available, and they cannot photosynthesize.

The euglena has a stiff pellicle outside the cell membrane that helps it keep its shape, though the pellicle is somewhat flexible and some euglena can be observed scrunching up and moving in an inchworm type fashion. Color the pellicle blue.

In the center of the cell is the nucleus, which contains the cell's DNA and controls the cell's activities. The nucleolus can be seen within the nucleus. Color the nucleus purple, and the nucleolus pink.

The interior of the cell contains a jelly-like fluid substance called cytoplasm. Color the cytoplasm light yellow. Toward the posterior of the cell is a star-like structure: the contractile vacuole. This organelle helps the cell remove excess water, and without it the euglena could take in some much water due to osmosis that the cell would explode. Color the contractile vacuole orange.

Which three of these development were major effector european colonization in africa

Answers

Answer:

More advanced medicine

Answer:

improvement in transportation and education systems. disregard for existing political or ethnic boundaries. promotion of free trade across countries.

Explanation:

1. Does a scientific theory ever become a law? Explain
the difference between scientific theory and law.

Answers

Answer:

a theory cannot become a law

Explanation:

the difference between a scientific theory and a scientific law because a theory is an in depth explanation of an observed phenomenon. a law is a statement about an observed phenomenon or an unifying concept (i.e.: newtons law or gravity - no explanation on how it works or what it is just that it exists.)

No a theory can not be a law

Sea turtles spend most of their lives at sea feeding on jellyfish. When it is time to lay their eggs, mature females come ashore. They dig
nests in the sand along the coast, lay their eggs, and then return to the sea. The data below show the changing sea levels since the late
1800s.

Answers

Answer:

this is not a very clear question T-T

Explanation:

wish i could help

Answer:

Explanation:

Afterwards, only females come ashore to nest; males almost never return to land ... Most females return faithfully to the same beach each time they are ready to nest. ... When the turtle has finished digging the egg chamber, she begins to lay eggs. ... Well over 90% of a sea turtle's life is spent in the water – feeding, mating, ...

How does the control group setup in an experimental differ from the other setups in the same experiment?

Answers

Answer:

A control group setup in an experiment is used to see if there are other variables in play during the experiment. Say I was to test which type of blood is a shark's favorite, my control would be putting red paint in one of the set ups to see if the shark is just interested in the red color of blood, instead of the other types of blood.

Explanation:

Answer:

The control group does not receive the independent variable during the experiment.

Explanation:

The group that will receive the independent variable during the experiment is the experimental group. The dependent variable is what you will measure as a result. The control group is not receiving the independent variable during the group, as it is what you're measuring the experimental group to.

Which of the following is an example of a lipid?
phospholipid.
triglyceride
fats and oils.
all of these

Answers

Answer:

phospholipid

Explanation:

Phospholipids, triglycerides, fats, and oils are examples of a lipid. Therefore, option D is correct.

What are lipids?

Fatty, waxy, or oily molecules are referred to as lipids. They are soluble in organic solvents but insoluble in polar solvents like water. Steroids, phospholipids, oils, and waxes are examples of lipids. They are usually referred to as fats and oils.

Since lipids may be broken down to provide significant amounts of energy, one of their primary biological purposes is the storage of energy. The structural elements of cell membranes and a number of the body's messengers and signaling molecules are also formed by lipids.

Cell membranes, cholesterol, blood cells, and the brain are just a few places where they can be found in the human body.

Learn more about lipids, here:

https://brainly.com/question/3498396

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Outermost solid layer of earth A:crust. B:mantle. C:outer core. D;inner core

Answers

Answer: crust

Explanation: The crust is the most outer layer sold layer of planet Earth. We live on the crust of the Earth. Therefore, crust is the answer.

Hope this helps!

An aquarium with a glass lid is an example of an isolated system.

true
false

Answers

Answer:

The answer is false!

Explanation:

I took the K12 science quiz.  I hope this helps! Have a blessed day! :)

The statement "An aquarium with a glass lid is an example of an isolated system" is false as light, air, and heat can transfer through the glass lid.

What is an aquarium?

An aquarium is an artificial place that is made for putting fish and other water animals in houses buildings and other places. Aquariums are made up of glass so can we, so we can see the fish's aquarium also have oxygen pumps the water also changed in the aquarium from time to time and. The aquarium is kind of decorative.

Aquariums are made up of glass, and they are open from the top so that fish can get air.

An aquarium is not an isolated system as light year and heat can transfer through the top and fishes are living organisms that need an open system to breathe and live.

Therefore, the statement is false.

To learn more about aquariums, refer to the below link:

https://brainly.com/question/21337200

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Which distribution pattern in species can be considered the most easily measurable

Answers

Answer:

local endemics

Explanation:

The most common distribution pattern in species can be considered by their geographical distribution, as different species get distributed as per their climate and the different regions that suit them the most.

What is the significance of the geographical distribution?

It is significant because they differ in different parts of the world and provide suitable climatic and other environmental conditions for various animals, plants, and microorganisms to live and evolve. Its significance can be seen in the difference between the life forms in the temperate area and those in the Antarctic area.

Hence, the most common distribution pattern in species can be considered by their geographical distribution, as different species get distributed as per their climate and the different regions that suit them the most.

Learn more about the geographical distribution here.

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-
Is salivary amylase a carbohydrate, lipid, nucleic acid or protein?

Answers

Answer:

Amylase

Explanation:

Select all of the following that describe RNA.
Check all that apply.
nucleotides contain the sugar deoxyribose
always occurs as a double-stranded helix
can be single-stranded
can catalyze chemical reactions
the nitrogenous base thymine is used instead of guanine
the nitrogenous base uracil is used instead of thymine
nucleotides contain the sugar ribose

Answers

Nucleotides contain the sugar ribose
Nucleotides contain the sugar deoxyribose
Can be single-stranded

The statements that describe RNA are ;

Nucleotides contain the sugar ribose ( 7 )Can be single stranded ( 3 )The nitrogenous base uracil is used instead of thymine ( 6 )

RNA and DNA are similar in some ways because they are both nucleic acids but the characteristics of RNA that makes it different from DNA is that RNA is mostly single stranded with it Nucleotides containing ribose instead of deoxyribose.

The RNA ( Ribonucleic acid )  nucleotides are composed of certain bases i.e. adenine, guanine, and cytosine also it contains uracil in place of thymine.

Hence we can conclude that the statements that describe RNA are ; Nucleotides contain the sugar ribose, Can be single stranded, The nitrogenous base uracil is used instead of thymine.

Learn more : https://brainly.com/question/13974826

Why do you think it is winter in the southern hemisphere while it is summer in the northern hemisphere?

Answers

The way the hemispheres and earths axis faces the sun changes so when the Southern Hemisphere is closer to the sun the northern hemisphere is further away as in getting colder

Answer:

yes

Explanation:

just to be nice could you mark this as brainleist please?

Happy Holidays!

Budding is a type of asexual reproduction. Which of the following is an disadvantage for asexual reproduction?

Answers

Disadvantages of asexual reproduction include: offspring compete for food and space, extreme temperatures can wipe out entire colonies, negative mutations can destroy many offspring.

True or False: A is the hanging wall and B is the foot wall.

Answers

Answer:

False

Explanation:

so they hanging walls above the plane of the fault (and over your head and the footwall is below the plane of the fault (and is under your feet)

Which type of rock does B represent?

Group of answer choices

Answers

I thing it is volcanic rock

which of these increases as greenhouse gases pollution increases
a.thickness of freshwater ice sheets
b. ocean salinity
c. ocean surface temp
d.rate of thermohaline circulation

Answers

Answer:

The answer is C.The ocean surface temp

Explanation:

I'm not sure of it but Greenhouse gases pollution raise the rate of Global warming so i think the temp one works the most

why do our digestive systems produce separate enzymes to digest proteins, fats, and carbohydrates?

Answers

Answer:

The digestive system produces different types of enzymes in order to convert proteins, fats and carbohydrates into smaller molecules and facilitate their absorption.

Explanation:

Once food is ingested, it must go through a process of digestion, which involves the conversion of food into smaller molecules, in order to facilitate its absorption at the intestinal level.

There are different enzymes, produced in the digestive system, for this purpose:

Proteases degrade meat proteins to convert them into amino acids. Lipases convert fats into fatty acids. Amylases convert sugars and carbohydrates into glucose.

The main objective is to obtain the fundamental components of each food to be assimilated by the organism, via intestinal absorption.

Question 1
The heat from a lamp allows a lizard to remain warm. This is an
example of which type of heat transfer?
Cold Blood
Conduction
Radiation
Convection

Answers

It definitely Radiation for the answer I think

Answer:

Answer is radiation

Explanation:

Took the test!

In science, which of the following best describes the scientific term
theory? *
A) An educated guess
B) An idea with lots of evidence to support it
C) possible idea that needs more evidence to be real science
D) An undisputed law that will not change.

PLEASE ANSWER!!!!!!!

Answers

Answer:

here's your answer

Explanation:

b) an idea with lots of evidence to support it .

In science, the word theory refers to a comprehensive explanation of an important feature of nature that is supported by many facts gathered over time. Theories also allow scientists to make predictions about as yet unobserved phenomena.

Observations:
In this photo I can
observe...
(delete this and start
typing here. See below
for ideas about what to
write about)

Answers

Answer:

In this photo, one can observe the big mountains, the clear blue sky, the sand which covers the ground, the path down the middle and the variety of dry, green plants.

Explanation:

^

particles is found in the nucleus of an atom

Answers

Answer:

protons and neutrons

Explanation:

Protons and neutrons have a positive and neutral charge, respectively. They are in the nucleus, while the negative electrons orbit the nucleus.

Answer:

Protons, neutrons, electrons

Explanation:

If you're asking about subatomic particles.



2. Which of the following does NOT contribute to globalization?
a) Countries protect their trade positions by increasing tariffs on foreign imports
b) Technological advances allow for decreased communications costs
c) Containerization makes international shipping inexpensive
d) Countries ratify new free trade agreements​

Answers

C) containerization makes international shipping expensive

Help me guys!! (Giving brainliest)

Answers

Answer: C

Explanation:

C because the cell membrane is semi permeable which means only certain substances can enter and exit.

Muscle cells contract using ATP. There is little ATP in your blood stream. How do your muscle cells get ATP they need to contract and move you?
1. ADP enters the cells from the bloodstream and it turns into ATP by adding a phosphate group in the nucleus
2. glucose from the bloodstream enters the cells and the mitochondria turns it into ATP
3. amino acids in the muscle tissue are broken down into ATP in the nucleus
4. glycogen from the bloodstream is turned directly into ATP by using enzyme glycanase

Answers

Answer:

I think its 1 or 2 my guy

Explanation:

I did this on some paper

Answer:

It's B

Explanation:

How does the formation of NAD+ differ between aerobic and anaerobic respiration?

A. NAD+ is formed in aerobic respiration by a fermentation process and formed in anaerobic respiration by oxidation of NADH.

B. NAD+ is formed by a fermentation process in anaerobic respiration by the conversion of pyruvate into lactate and by simple oxidation of NADH in aerobic respiration.

C. Under aerobic conditions, the electron acceptor is a molecule other than oxygen for NAD+ production, whereas under anaerobic conditions the electron acceptor is oxygen.

D. NAD+ is formed by the breakdown of pyruvate to form oxaloacetate in anaerobic respiration whereas in aerobic respiration it is formed by the breakdown of pyruvate into lactic acid or alcohol.

Answers

Answer:

B. NAD+ is formed by a fermentation process in anaerobic respiration by the conversion of pyruvate into lactate and by simple oxidation of NADH in aerobic respiration.

Explanation:

Nicotinamide adenine dinucleotide (NAD) is an important coenzyme that may exist in two different forms: oxidized (NAD+) and reduced (NADH). The fermentation is an anaerobic oxidation-reduction reaction where pyruvate and NADH are reactants, while lactate and NAD+ are products generated by the oxidation of NADH to NAD+ and pyruvate to lactate, respectively. On the other hand, during aerobic respiration, NADH generated by glycolysis is oxidized to form NAD+ by the donation of its electrons to reduce pyruvate to lactate. Subsequently, NAD+ is reused in glycolysis (again) in order to generate more molecules of ATP.

identify and describe one natural and one man made source of carbon in the carbon cycle?

Answers

Greenhouse effect is the answer
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